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No clinically significant differences between aspartame and placebo were found for the STESS,MIT,or Conners ratings,or for the MFFT,CCT,WCST,or Airplane cognition tests.Also,no differences were noted for any of the biochemical measures,except for the expected increase in plasma phenylalanine and tyrosine following aspartame.The findings indicate that aspartame at greater than 10 times usual consumption has no effect on the cognitive and behavioral status of children with attention deficit disorder.In addition,aspartame does not appear to affect urinary excretion rates of monoamines and metabolites. |
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